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You can buy the various tadalafil dosages available under the trade name Cialis, among others. But what is tadalafil? This medication is used as a treatment of certain sexual dysfunctions, such as sexual impotence. Approved for medical use in the United States 18 years ago, these tablets have other therapeutic benefits in addition to inducing erections. However, the induction and maintenance of the penile erection is the primary function of these pills. Sexual impotence is a common sexual disorder among men of any age. There are many causes for the onset of this dysfunction, with the most common being blood circulation and hypertension. There are additional reasons for one to develop difficulties associated with the erection process and these can include:

  • Diabetes: this is a medical condition characterized by high blood sugar levels. Diabetes is a common health ailment affecting millions of people around the world. It was suggested that the prevalence of this disease was 10.5% of the American population, three years ago. Diabetes contributes to ED because the condition is known to damage the nerves and blood vessels.
  • High cholesterol: you are considered as having high cholesterol when your body has too much LDL cholesterol (or low-density lipoprotein). This is often referred to as the 'bad cholesterol' and if left untreated, can lead to numerous health complications. Increased LDL in the blood can affect the flow of blood to the penis, and hence result in sexual impotence.

You can easily buy this medication online, but before you do, let is explain what is tadalafil indicated for. It is these vasodilating medications that assist in improving blood flow to the penis and thus relieve the symptoms of ED.

What is Tadalafil Used for?

Tadalafil is used for:

  • Erectile dysfunction: taken once a day, these tablets may be useful in managing the symptoms of ED, and that includes assisting one in achieving an erection as well as maintain said erection. Impotence can be categorized as intermittent (occasional) or complete. Occasional ED generally affects men for a short period of time and can be related to stress or exhaustion. On the other hand, complete impotence may be related to a medical condition and the consequences thereof, such as damage to the cardiovascular system.
  • Pulmonary arterial hypertension (PAH): this is a disease where the patient has high blood pressure in the arteries of the lungs. This is a progressive condition which means that it will most likely worsen over time, however, the use of this erectile dysfunction medication can assist to lessen the symptoms of PAH. Those with this medical ailment can develop clots in the pulmonary arteries and this may restrict the flow of blood, thus adversely affecting the blood circulatory system. A dose of 40 mg of generic Cialis is approved in the U.S., Japan and Canada for the treatment of PAH.
  • Benign prostatic hyperplasia: this is a condition which involves urinary difficulties because of an enlarged prostate gland and is normally an age-associated disease. This type of prostate enlargement is different to the prostate enlargement related to cancer. Evidence shows that a 5 mg dosage of these sexual dysfunction tablets can help relieve the urinary tract symptoms of this ailment.

How Does Tadalafil Work?

An erection occurs when the blood vessels within the penis widen, blood then enters the arteries to fill them and after getting trapped in the penis, this blood is under pressure hence causing the penis to stiffen and become erect. Those with sexual impotence have difficulties in achieving this erection and maintaining the erection after it has been acquired. There are many reasons for these difficulties but the inability to achieve an erection often has dire consequences on the sexual health, relationships and other aspects of the patient's life.

For those who are experiencing these sexual difficulties, it is advised that one buy tadalafil tablets for the management of these symptoms. These tablets are effective in inducing and maintaining erections so that the quality of the sex life of the patient may be restored.

Tadalafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). Through the inhibition of this enzyme the flow of blood to the penis increases and therefore the erection process can occur. The mechanism of action is not well-known but research has suggested that this vasodilating tablet has the ability to relax the smooth muscles and arteries thereby making them efficient at blood flow. For those with ED, these pills can relax the muscles in the penis, likewise for those with PAH, these tablets may be useful to relax the smooth muscles in the chest area. The ultimate consequence of this action influences the blood circulatory system.

How Long Does Tadalafil Last?

There are countless reasons why more men search for this medication, and according to reviews and FAQs, most ask how long does tadalafil work for between doses?  

  • These tablets, like other PDE5 inhibitors, all work to improve blood flow but the main difference between these therapeutics is the duration of action. Tadalafil lasts for approximately 17.5 hours as compared to sildenafil and vardenafil (similar PDE5 inhibitors) which last for less than half the time. This is probably the most distinctive pharmacological difference among the medications for ED.
  • The relatively long duration of action is also the reason for the therapeutic use of this medication for the treatment of PAH.
  • Although it is not commonly used for the treatment of premature ejaculation (a sexual dysfunction where one reaches orgasm before initiating intercourse or less than a minute after sexual activity), this medicine has been reported as being useful for this purpose. Karabakan et. al. (2017) reported the use of a 5 mg dose on a daily basis to increase ejaculatory times, in addition to assisting in the management of urinary tract and ED symptoms.

    This research was conducted over three months on 60 clinical trial ED patients, and significant improvements were observed in the intravaginal ejaculation latency times (time it takes to reach orgasm during sexual intercourse), international prostate symptoms scores as well as the scores of the international index of ED questionnaire.
  • The duration of action of these tablets are, however, not the same for each individual. There are various factors that may increase of decrease the time of therapeutic action of this medication.

Tadalafil Dosage Guide

The most popular tadalafil dosage is 20 mg and is generally well-tolerated by patients. Each dose comes as a film-coated tablet containing 20 mg of the active ingredient. They are typically marketed as yellow, capsule-shaped tablets debossed with 'T20' on one side of the pill. Tadalafil 20 mg can be effective for the treatment of sexual impotence and for the management of hypertension associated with the arties of the lungs too (a 20 mg dose taken twice a day).

10 mg of this active ingredient are normally used as a starting dosage when treatment is initiated and if the medication is tolerated well, this dose may be increased. However, in the event of side effects, this dose may be reduced to 5 mg. Tadalafil 10 mg tablets are similar in appearance and formulation to the 20 mg pills except these tablets are formulated with 10 mg of the active ingredient, are light-yellow in color and debossed with 'T10' on one side.

Tadalafil 5 mg is the lowest available dosage and is generally not prescribed for treating erection problems. However, there are some studies which have shown otherwise, such as the research study previously mentioned. This dose may be useful for the management of PAH and benign prostatic hyperplasia. A lower dosage tablets, such as this, is normally advised for senior patients as this minimizes the risk of developing side effects. In addition, those with renal or hepatic dysfunctions may benefit from this low dosage therapeutic as these patients can experience impaired drug elimination. These tablets are circular, bi-convex, film-coated pale pinkish yellow pills that are debossed with 'T5' on one side.

Tadalafil Side Effects

Side effects, also referred to as adverse effects or adverse events, are the secondary actions of a therapeutic in addition to its intended medical purposes. These are generally undesired or unwanted symptoms but there are some cases where the side effects may be useful, such as those that reduce blood pressure which may be useful for hypertension patients.

Tadalafil side effects are typically known to be mild in severity and short-lived as well. Some of the adverse effects can include:

  • Facial flushing
  • Headaches
  • Runny nose
  • Stomach discomfort or pain
  • Back pain
  • Vision and hearing impairments

According to scientific research, the tadalafil side effects reflect the ability of these vasodilating medicines to function and normally resolve within a few hours. Specifically, the back pain adverse event normally occurs 12 to 24 hours after taking a tablet and these symptoms usually disappear within 48 hours of onset. The Food and Drug administration (FDA) conducted studies which drew an association between the use of this medication and vision impairment related to the loss of blood flow to the optic nerve but after further research the health agency stated that they were unsure of a relationship between the two. In spite of this conclusion, vision and hearing impairments have been observed among those using the therapeutic though it is unclear why this may occur.

Tadalafil vs Sildenafil

  • There are many studies which review tadalafil vs sildenafil, but the most prominent difference between these medications is the duration of action. How does tadalafil work differently? Where sildenafil tablets may last from four to eight hours, this medication lasts longer (for 17.5 hours and up to 36 hours, in some cases).
  • These tablets remain a popular choice because the extended duration of action allows for sexual spontaneity. This means that the user does not have to time sexual activity as much as they would have to when using sildenafil pills. The long-lasting effects of this medication allows for one to engage in sexual activity with less restrictions associated with the duration of therapeutic action of the medicine.
  • According to tadalafil reviews, most people favor this medication over other PDE5 inhibitors because of its cost effectiveness. In addition to the prolonged therapeutic action, the tadalafil cost is an added benefit of the medicament. This is especially significant in situations where the patient is on a regular treatment schedule and has to take the tablets on an everyday basis. For those who frequently buy this medication, this would be the most sensible option as it would provide the necessary treatment that would not have to be discontinued because of the high cost of the therapeutic.
  • Despite the pharmacological difference and the cost of these medicaments, evidence has revealed that these therapeutics share similar safety and efficacy as well as the ability to improve the sexual confidence of the patient.

Buy Tadalafil Online

Now that you know what is tadalafil and how easy it is to obtains, you can see that online pharmacies are an appropriate way of comparing medications, especially those who form part of the PDE5 inhibitor family. When you buy this medication through online portals, the comparison of these medicaments is not only limited to the cost but to the effectiveness of these therapeutics as well. There are user reviews available that offer insight to the personal experiences of patients. These reviews provide details pertaining to the use, side effects as well as other aspects of the medication.

Another reason to acquire tadalafil online is that the topic of impotence may be a sensitive issue. Many men are deterred from seeking treatment for their symptoms of ED because they are unwilling to discuss the details of their condition with someone in person. Using online platforms may be the most useful way of maintaining your privacy when buying medicines for the treatment of impotence.

You can find this medication for sale in varying strengths and dosages at Wizz Pharmacy. However, when using these tablets, it is important that you are first diagnosed with sexual impotence and not using the medication for another other reason. To be diagnosed with ED there are certain criteria which have to be met prior to you being allowed to start treatment. These criteria can be accessed by an online doctor and are often related to the frequency and severity of your symptoms.

This medication is neither a cure for ED nor does it increase sexual desire, but it is rather a safe an effective way to management the symptoms of impotence and restore good sexual health.

Dr Sophia Miller
Medically Review by:

Dr Sophia Miller

Dr Sophia Miller was born in New York City, USA. As a young woman, she was always interested in science, specifically; chemistry and she was determined to pursue a career in the field.

Checked: 15th March 2023
Review Due: March 2024


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