Vardenafil

What is Vardenafil 20 mg?

These are vardenafil tablets formulated with 20 mg of the active pharmaceutical ingredient (API). A 20 mg dose is sufficient for the average man (without hepatic or renal impairment) to use safely for the attainment, or maintenance, of the penile erection. Vardenafil 20 mg is approved for the treatment of erectile dysfunction, but this medication has also been shown to be useful, off-label, for the management of premature ejaculation (PE) symptoms. PE is another common sexual disorder that affects men and is estimated to impact about 4-39% of the general male population.

PE occurs when a man is unable to control their ejaculatory responses. The symptoms of this condition occur when a man, soon after penetration, reaches orgasm and subsequently ejaculates. PE can happen within less than a minute of achieving an erection therefore leaving one to feel dissatisfied and frustrated as well. This erectile dysfunction medication is available 24-7 via reputable online pharmacies, which makes it convenient seeing that you cannot buy vardenafil over the counter at a physical store. It is considered highly efficacious in prolonging ejaculation during sexual intercourse, making it increasingly sought after.

In a randomised, cross over study, the effects of this medicine were evaluated in men with an IELT (intavaginal ejaculation latency time) of less than 1.30 minutes. These clinical trial patients were chosen based on the ineffectiveness of behavioural therapies on their PE symptoms and were reported to have experienced significant improvements in their IELTs (Mathers et. al., 2009).

Branded or generic Levitra can hence, be beneficial for both impotence and premature ejaculation as well.

How Does Vardenafil Work?

The mode of action of these erectile dysfunction pills have not been fully established but it is thought that this medicine assists in relieving erection problems through the following:

• Once administered, these tablets are broken down, through the digestive processes, to release the API, which is subsequently absorbed by the bloodstream.
• Following absorption by the body, the therapeutic ingredients in the medication inhibit the action of the phosphodiesterase (PDE5) enzyme.
  
  PDE is an enzyme that breaks down cGMP in the body. cGMP is the component that relaxes the smooth muscles and dilates blood vessels.
• Through the inhibition of PDE5, cGMP is allowed to increase and function unrestricted. This means that the cGMP compounds in the body widen the blood vessels and the subsequent flow of blood through the arteries is thereby enhanced.
• When blood flows to the penis unimpeded, the erection process can occur and be maintained for sexual intercourse. Essentially, vardenafil works by improving blood flow to the penis so as to accomplish this intent.

The previously mentioned process happens rapidly after the API enters the bloodstream, but this cannot be experienced if there is no sexual stimulation. Sexual arousal is a pre-requisite of the functioning of this medication because it releases nitric oxide. The nitric oxide chemical is required for the penile muscles to relax.

How Long Does Vardenafil Take to Work?

Onset of action: this is the time it takes for a medication to take effect. The onset of action of this therapeutic is relatively short as vardenafil takes approximately 30 minutes for the benefits to come to prominence. This time to therapeutic action is generally indicated in the information leaflets when you buy vardenafil.

Factors that can affect the onset of action:

• Foods: certain foods, such as those rich in fats, may delay the time it takes for a medication to work. For a medicine to work, the therapeutic has to be digested and absorbed by the bloodstream. High-fat meals prolong therapeutic action as they delay gastric emptying (this is the process by which the stomach contents are moved to the small intestine).
• Lack of sexual arousal: sexual stimulation is imperative for this ED medication to function. If not sexually aroused, the tablets cannot take effect.
• The time taken to consume the medication: as previously mentioned, the medicine has to be first processed through the digestive system for the API to be absorbed by the bloodstream. For this to occur, the pills have to reach the stomach where it can be processed. Water is normally administered with a tablet as it aids in the transport of the medicine to the desired destination in the body. By not drinking adequate water, the medication may get lodged in the oesophagus and not reach the stomach quick enough, and this may consequently, delay the therapeutic action.

Vardenafil Dosage Guide

The right dosage of a medication is essential as it is an individualised dose, specific to you and your body. Factors, such as your age, health condition and body size, are taken into account when an amount of therapeutic is recommended to you.

The recommended vardenafil dosage is 10 mg, this is as you begin using the medication. The initial standard dose can be adjusted upward or down depending on your response to the medication. If you feel as though you are reaping the benefits of the medicine and can tolerate a higher amount, then you may increase this dosage to 20 mg. However, it is always best to increase your dosage with advice from a medical advisor. In the event of severe side effects, it would be best to reduce your dosage to 5 mg.

A vardenafil 20 mg dosage is usually well-tolerated but best suited to younger men, without any liver or kidney dysfunctions. For older men, a lower dose would be advised as the renal elimination process can be impaired in seniors thus prolonging the time it takes to remove the therapeutic from the body. This medication may be taken anywhere from 25 to 60 minutes prior to sexual intercourse and with or without food, although without food is preferable.