Impotence can be an indication of a physical or physiological condition and patients with ED should ideally address underlying medical problems long term, while treating the sexual dysfunction immediately. These ED tablets were originally co-marketed by the pharmaceutical companies, Bayer Pharmaceuticals, Schering-Plough and GlaxoSmithKline (GSK), but as of 2005, the co-promotion rights of GSK were returned to Bayer in many locations outside the United States. In Italy, Bayer Pharmaceuticals market these tablets as the brand, Levitra but GSK sells this medication as Vivanza.
Vardenafil generics (named after the active ingredient of the above treatment) are identical to the brand version and are also used for the treatment of erection problems. The latter issues being associated with the inability to achieve and / or maintain an erection. Commonly known as sexual impotence (or ED), this sexual disorder can affect men both young and old. The need for this therapeutic and the prevalence of this sexual health condition is therefore great, in all parts of the world. In a 2018 review, it was suggested that at least one third of men were affected by ED. Furthermore, the prevalence of complete impotence was reported to increase by 5% for men at the age of 40 years and 15% for men at 70 years.
Levitra is primarily used for the management of erectile dysfunction as it is known to improve the blood flow to the penis through the dilation of the penile blood vessels. This widening of the blood vessels occurs through the therapeutic action of the relaxation of the arteries. Although, this erectile dysfunction medication is only approved for the treatment if impotence, these pills have been revealed to also have an effect on high blood pressure, according to FDA (Food and Drug Administration) research.
Clinical trials, reported by the FDA, investigating the use of these pills for ED also indicated that single dosages of 20 mg Levitra reduced both systolic and diastolic blood pressure as well. This could suggest that the therapeutic may be useful for the treatment of hypertension but this medical use has not been indicated as such. Beyond its indications of sexual impotence, these sexual dysfunction pills have been shown to have a significant effect on the time from penetration to ejaculation, and hence the treatment of premature ejaculation.
The mechanism of action of this medication is complex, but these pills essentially function to influence the blood circulatory system. Levitra is classified as a PDE5 inhibitor, also known as a phosphodiesterase type 5 inhibitor. Classified as such, vardenafil works to inhibit the action of the PDE5 enzyme.
PDE is responsible for the metabolism (breakdown) of the substance cGMP but cGMP is thought to inhibit smooth muscle contraction (or in other words, promote muscle relaxation), and it is through this action that the blood vessels are dilated allowing for more blood is pass through. By inhibiting the metabolic activity of PDE5, the action of cGMP can be enhanced and the flow of blood to the penis may be potentiated.
The therapeutic action of Levitra can also delay ejaculation after the penile erection by increasing the intravaginal ejaculation latency times), improved ejaculatory control and enhanced overall sexual satisfaction in men with premature ejaculation (Aversa et. al., 2009).
Levitra pills take approximately half an hour for the benefits to come to prominence and the therapeutic action of this medication can last for about four hours. However, this duration of action may be longer for some men, according to vardenafil reviews.
Factors that may affect the therapeutic action of Levitra include:
The standard advised vardenafil dosage is 20 mg. However, the typical dose when initiating treatment is 10 mg. This allows you to determine if the medication is well-tolerated by the body and if it is safe to increase the dosage. If not tolerated by the body, the initial dosage may be reduced to minimise the risk of side effects. Levitra is convenient as this medication is available in a wide range of strengths, namely:
However, the best dose of Levitra for you depends on your:
When using this medication, it is recommended that you administer the tablets at least half an hour before you anticipate sexual activity. This can be done by simply swallowing the pills with a drink of water, before or after a meal (although, before a meal is preferred so as to not the delay the onset of action).
One of the most frequently reported vardenafil side effects is blurry vision or change in colour perception in the eyes. This alteration in vision is a widely know side effect of this ED medication as well as other popular tablets that treat impotence. In a study investigating the ocular side effects of Levitra, Roesseler et. al. (2019) reported that the change in vision was attributed to temporary alterations in retinal function in those using the medication.
This review involved 24 healthy male subjects and the single dose administration of two 20 mg pills. There were ocular adverse events reported by the study population albeit none serious or severe in nature. These researchers concluded that in spite of the temporary changes in retinal function, the tolerability of this therapeutic was found to be good.
Other side effects associated with the use of Levitra include:
Typically, clinical trials have suggested that these side effects are mild to moderate in severity and tend to last only a short while. However, if you experience these effects in greater severity, you can consult a healthcare professional for a possible treatment plan.
You can use our online pharmacy for the safe and secure purchase of erectile dysfunction pills. To buy Levitra, you simply have to search for the medication on our website and select the dosage and quantity of product you require. However, if you would like to buy an alternative to this medication, such as a Levitra generic medication, you can do so in the same manner as you would when buying the branded therapeutic.
Generic formulations are sometimes preferred over the brand name medications as they tend to be more cost-effective (they can be up to 85% cheaper in some cases) but still maintain the level of efficacy as the original version. Whether you choose to use the genetic or the branded form of these ED pills, you can find any treatment you are looking for here.