Wizz Pharmacy Logo

How Does Dapoxetine Work?

  • By: Dr Sophia Miller
  • Jun 25, 2021
How Does Dapoxetine Work?

This is a highly effective treatment for the male sexual disorder, premature ejaculation (PE), and is commonly used by men aged 18 to 64 years. These tablets were created to help men increase their ejaculation times by affecting the hormone, serotonin. This mechanism of action is similar to that of an anti-depressant medication, but due to the fast-acting formulation of this therapeutic, dapoxetine was better suited to being a sexual dysfunction medicine rather than an anti-depressant.

So to answer, how dapoxetine works, the active ingredient in these tablets is dapoxetine, which is a therapeutic substance classified as a selective serotonin reuptake inhibitor, or SSRI. When we feel happy, anxious or moody, it is the serotonin hormone that stabilizes these feelings. Moreover, this hormone also impacts other body processes, such as digestion, sleep or ejaculation, by affecting the communication between nerve and brain cells.

Following the communication of a chemical message, serotonin is typically reabsorbed by the nerve cells in what is known as a 'reuptake' of the hormone. By blocking this reuptake process, the levels of serotonin can subsequently be increased and thus, more readily available for influencing the physiological process of ejaculation. Dapoxetine (Priligy) tablets therefore work, through the above-mentioned process, to treat ejaculation problems by increasing the time to sexual climax.

Are you trying to find out how does dapoxetine work? Maybe you are interested in learning how long until dapoxetine works? Perhaps you have heard how fast dapoxetine works and want to know more? If you have found yourself asking these questions, you can find the answers as you continue reading.

How Does Dapoxetine Work to Treat PE?

Many new patients ask how this medication functions so they can get a better understanding on what they can expect before they place an order. To answer this common question, here is a brief explanation. A dapoxetine dosage is normally used by men who are experiencing symptoms of acute to chronic premature ejaculation

There are certain criteria that determines if men have PE, which includes;

  • An intravaginal latency time (IVLT) of less than two minutes
  • Ejaculation that occurs recurrently, with minimal sexual arousal, and sooner than the patient would prefer
  • Lack of control over ejaculation
  • Persistent symptoms of PE occurring for at least a period of six months
  • Interpersonal strain or problems as a consequence of the PE symptoms

For men who are experiencing all of the above criteria, they often wonder how does dapoxetine work as a premature ejaculation treatment. Research indicates that the way  dapoxetine 60 mg functions as a selective serotonin reuptake inhibitor increasing serotonin levels in the brain. The effects of this explain, how does dapoxetine work to treat symptoms of PE by:

  • Increasing the IVLT to an average of 3.8 minutes; ranging from 0.9 to 4.7 minutes (McCarty and Dinsmore, 2012)
  • Improving control over ejaculation
  • Improving ejaculation-related distress and other negative consequences
  • Improving sexual satisfaction

How Long Until Dapoxetine Works?

To answer how long until dapoxetine works, these oral tablets contain this active ingredient that rapidly absorbs into the bloodstream after administration. In most cases, this on demand treatment absorbs almost immediately after ingestion and within as little as 30 - 60 minutes reaches maximum effects. At full potency, this medication is most effective for the first 1 - 3 hours and often remains active in the body for around 12 - 18 hours. Before taking a dose, avoid eating heavy foods because doing so may delay the onset actions and reduce the overall efficacy.

Avoiding heavy foods when taking a dose is advised, but there are foods that help control onset ejaculations and enhance sexual performance. Studies show that eating foods like oatmeal, eggs and leafy greens are rich sources of folic acid and essential vitamins help prolong onset ejaculations. There are other measures patients can take before consumption that helps avoid any delays is absorption and activation. 

Blood flow is important for sexual function and staying hydrated helps to maintain peak muscle and organs strength, which helps control ejaculations. Research suggests behavioral techniques like masturbation before sex and the stop-start method shows promising results, allowing men to engage in longer lasting intercourse. Men from all over the globe choose this medication because of how fast dapoxetine works to increase their time in the bedroom and improve sexual health.

How Long Will Dapoxetine Work for?

Dapoxetine tablets are fast-acting SSRI; this means that the therapeutic ingredients are rapidly absorbed by the body. These pills should ideally be taken at least one to three hours prior to sexual activity as this will give the medication sufficient time to work in the body before it is required to increase the time to ejaculation. how long dapoxetine works can depend on the individual but in most cases, the effects can last for approximately 12 hours. There are some aspects like underlying medical condition, the dosage used and many other factors that may slightly affect the outcome.

Therapeutic benefit has been observed with the use of this premature ejaculation medication for up to 12 weeks, according to researchers. However, if patients use this medicine in the long term, doing so can also be associated with an increased risk of side effects, including:

  • Nausea
  • Headaches
  • Dizziness
  • Decreased libido
  • Dry mouth
  • Insomnia
  • Erectile dysfunction
  • Diarrhea

As per a study by McMahon (2012), the incidences of adverse effects were reported as being dose-related. The most common adverse events were headaches (5.6% for the 30 mg dose, 8.8% for the 60 mg), nausea (11% for the 30 mg dose, 22.2% for the 60 mg dose) and dizziness (5.9% for the 30 mg dose, 10.9% for the 60 mg dose). Moreover, when taken as needed, the dapoxetine side effects, such as a decreased libido and sexual dysfunction, were shown to be very mild in nature (less than 1% and 4% of the clinical trial patients, respectively).

Does 30 mg and 60 mg Dapoxetine Work Differently?

The mode of action of dapoxetine and how quickly dapoxetine works remains the same, irrespective of the dosage, but it is the effects, of these doses on the body, that may vary. As previously mentioned, higher dosages of a medication can be related to a higher incidence of side effects. However, with that said, a higher dose can also be associated with greater therapeutic benefit.

In a clinical trial of 2614 men with moderate to severe symptoms of PE, a 30 mg dosage was revealed to increase the time to ejaculation to a mean 2.78 minutes, as compared to a mean of 3.32 minutes for the 60 mg dose of the premature ejaculation pills. This was following a three-month treatment period, which indicated an IVTL of an average 1.75 minutes for the placebo (inactive treatment) group of the study population.

Furthermore, according to the previously mentioned study by McCarty and Dinsmore, the half-life (time taken for the removal of half of the medication from the body) is longer for the 60 mg dosage (21.9 hours), as compared to a half-life of 18.7 hours for the 30 mg dose. This further indicates how long dapoxetine works at greater efficacy of the higher dosages through a prolonged duration of action.

Many men are in favor of the 60 mg dose of this medication, as per a dapoxetine review, and this is also a frequently reported or standard dose of treatment. But for men who are at a greater risk of developing adverse effects (such as seniors or those with renal and/ or hepatic impairment), a 30 mg dosage may be a better suited when initiating dapoxetine treatment. You can easily find dapoxetine for sale, in both 30 mg and 60 mg dosages, through secure online pharmacies.

Buy Dapoxetine Last Longer in Bed!

A safe and secure online pharmacy is quickly becoming the norm for buying medications because of its ease and convenience of use, in addition to the vast other benefits these platforms offer. The internet pharmacy phenomenon is particularly useful for those with sensitive issues, such as premature ejaculation, as they provide a discreet means of acquiring treatment. Like men around the world have done already, you can conveniently buy dapoxetine online via our secure e-pharmacy.

When shopping with us, you maintain complete privacy throughout the process with a level of anonymity that would typically encourage patients to seek information about medications (that they would otherwise feel too ashamed to ask a general practitioner about). There is no need to face potential embarrassment now that you can make a purchase without prescription or goings to the local chemist. Placing an order from our homepage by selecting the medication and quantity you want before heading to the checkout. 

Enter a valid phone number, email ID and delivery address before completing your payment using Bitcoin (BTC), VISA or a MasterCard. An email is sent outlining the inconspicuous descriptor name indicated on your financial statement, confirmation of payment and the estimated delivery date upon receiving payment. Orders are packed into discreet envelopes and dispatched within 24 hours. Home deliveries take about 5 - 7 working days worldwide. Contact our 24/7 client support services via phone, live chat or email if you require further assistance and our team are happy to help.

Buy dapoxetine pills through our established internet pharmacy and join the millions of men who use this safe and effective FDA approved treatment to last longer in bed.

Dr Sophia Miller
Medically Review by:

Dr Sophia Miller

Dr Sophia Miller was born in New York City, USA. As a young woman, she was always interested in science, specifically; chemistry and she was determined to pursue a career in the field.

Checked: 15th March 2023
Review Due: March 2024

Rate this Post

Your email address will not be published.
Required fields are marked *

  • Your rating